A protective cover for use as a liquid barrier includes an enclosure comprising a supported front sheet and a back sheet, said enclosure made of a flexible, liquid impervious material, the back face having a periphery in the interior of the back face that defines an opening and an adhesive layer extending along the periphery of the back face for securing the periphery onto a body part, wherein the periphery is positioned and sized to define an opening that can accommodate a body part to be shielded from liquid.