ANTICANCER COMBINATION OF ARTEMISININ-BASED DRUGS AND OTHER CHEMOTHERAPEUTIC AGENTS

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专利权人:

SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.

发明人:

PISANO, CLAUDIO,VESCI, LOREDANA

申请号：

SG2012032991

公开号：

SG180703A1

申请日:

2010.12.06

申请国别(地区):

SG

年份:

2012

代理人:

摘要：

The present invention relates to combinations between artemisinin-based potent anti-malarial agents, selected from the group consisting of ART, DHA and ARM, and a further chemotherapeutic drug selected from the group consisting of a camptothecin derivative, or a PARP-1 inhibitor, or an intercalating DNA agent, or an alkylating agent. Such combinations, showed medium to strong synergism in various models of cancer, in particular in NSCL.

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