Давыдов Евгений Владимирович (RU),Коробов Сергей Сергеевич (RU)
申请号：
RU2015116336
公开号：
RU2015116336A
申请日:
2015.04.29
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. A method for fluorescence diagnosis of cancer, comprising using a photosensitizer, the main active substance is Chlorine E6, administered intravenously, and Dimegina accumulation of photosensitizers in malignancies ray irradiation wavelength corresponding to the absorption wavelength of photosensitizer, registering and comparing the fluorescence intensity obtained from areas of cancer and from healthy tissue, characterized by the fact that the selected Photoditazine Dimegin and intravenously administered in a random order at a ratio of 3: 1 ... 1: 5, for selecting dose administration photodithazine in the range of more than 1.5 mg / kg and not more than 2.5 mg / kg body weight, and for Dimegina in the range of 0.5 mg / kg ... 2.0 mg / kg body weight, with the accumulation time selected over 90 min, and the radiation dose of 0.01 J 3 J ... at a radiation power of 50 mW ... 100 mVt.2. Method fluorescence diagnostics of cancer according to Claim. 1, characterized in that the selected accumulation time 120 ... 240 min.3. Method fluorescence diagnostics of cancer according to Claim. 1, characterized in that the irradiation is carried out at the wavelengths 390 ... 410 nm.4. Method fluorescence diagnostics of cancer according to Claim. 1, characterized in that the irradiation is carried out at the wavelengths 600 ... 630 nm.5. Method fluorescence diagnostics of cancer according to Claim. 1, characterized in that irradiation is performed at wavelengths of 650 nm ... 670 nm and 390 nm 410 nm ... odnovremenno.6. Method fluorescence diagnostics of cancer according to Claim. 1, characterized in that irradiation is performed at wavelengths of 650 nm and 670 nm ... 600 ... 630 nm odnovremenno.7.1. Способ флуоресцентной диагностики злокачественного новообразования, включающий использование фотосенсибилизатора, основным действующим веществом которого является Хлорин E6, вводимого внутривенно, и Димегина, накопление фотосенсибилизаторов в злокачественном новообразовании, облучен
