The present mventıon relates to topical pharmaceutical compositions comprising flurbiprofen or a pharmaceutically acceptable salt thereof and methyl salicylate More specifically, the invention relates to topical pharmaceutical compositions of flurbiprofen and methyl salıcylate characterized m that said composition compnse dımethyl sulfoxıde and one or more gelling agent. Furthermore, the invention relates to process for prepanng the saıd topical pharmaceutical compositions and its use for the treatment of pam and ınflammatory symptoms associated vvith muscle-skeletol system, joint and soft-tissue disorders.
