SMITH, ERNEST S.,ZAUDERER, MAURICE,BOWERS, WILLIAM J.,JONASON, ALAN
申请号：
CA2927841
公开号：
CA2927841A1
申请日:
2014.10.21
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Provided are methods for alleviating symptoms in a subject having a neurodegenerative disorder, comprising administering to the subject an effective amount of an isolated binding molecule which specifically binds to semaphorin-4D (SEMA4D) or to its Plexin-B1 or Plexin-B2 receptors. Further provided is an isolated binding molecule which specifically binds to the same SEMA4D epitope as a reference monoclonal antibody selected from the group consisting of VX15/2503 and 67.
