Smith, Ernest S.,Zauderer, Maurice,Bowers, William J.,Jonason, Alan
申请号:
AU2014340210
公开号:
AU2014340210B2
申请日:
2014.10.21
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Provided are methods for alleviating symptoms in a subject having a neurodegenerative disorder, comprising administering to the subject an effective amount of an isolated binding molecule which specifically binds to semaphorin-4D (SEMA4D) or to its Plexin-B1 or Plexin-B2 receptors. Further provided is an isolated binding molecule which specifically binds to the same SEMA4D epitope as a reference monoclonal antibody selected from the group consisting of VX15/2503 and 67.