David M. Markovitz,Nirit Mor-Vaknin,Michael Khodadoust,Barbara S. Adams
申请号：
US12090164
公开号：
US08652467B2
申请日:
2006.10.16
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to DEK protein compositions (e.g., antibodies, small molecule inhibitors, siRNAs) and methods of using the same. In particular, the present invention provides compositions and methods for treating autoimmune disease (e.g., juvenile rheumatoid arthritis, lupus, etc.) and for inhibiting inflammation (e.g., associated with autoimmune disease) and cellular chemotaxis (e.g., of neutrophils, NK cells and T cells). The present invention further provides a diagnostic marker (e.g., DEK antigen) for autoimmune disease.
