Inhibitors of lethal factor protease

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专利权人:

Burnham Institute for Medical Research

发明人:

Pellecchia, Maurizio

申请号：

AU2008229726

公开号：

AU2008229726B2

申请日:

2008.10.01

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

#$%^&*AU2008229726B220141002.pdf#####ABSTRACT The invention provides compounds that can efficiently and specifically inhibit 5 bacterial toxins, such as inhibit the lethal factor (LF) protease activity of anthrax toxin and/or botulinum neurotoxin type A. The invention also provides methods for inhibiting proteases, such as lethal factor protease, as well as methods for treating bacterial infections, such as anthrax and botulinum. 10

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