4. A derivative from tetrahydropyridine [3, 2-F] [1, 4] oxazepin-8-amine, pharmaceutical component 1: a formula compound (1), wherein R1 is selected from hydrogen, c1-3, - C (o) CH3, - ch2och3, - C (o) n (CH3) 2 and - ch2cn； R2 is selected from c2-4 tar (optionally replaced by one or more selected alternatives independent of fluorine and hydrogen XI),1. Phenyl, 5 or 6-member isopentadiol, c3-6-type carbohydrate and c4-6-type isoprene (wherein phenyl, 5 or 6-member isopentadiene, c3-6-type carbohydrate and c4-6-type isopropene can be replaced by one or more substitutes independent of halogen, c1-3 and alcox c1-3)；R3 is an unorthodox group composed of 5 or 6 members consisting of at least one nitrogen atom. In this group, the unorthodox group of 5 or 6 members can be replaced by one or more substitutes that are hydrogen, methoxi or cyanogen independent of c1-3, chlorine, oxo, CH2OH, ch2och3, chf2 and ch2f, R4； R 5 is hydrogen or fluorine； R 6, R7 and R 8 are separated from hydrogen and c1-3 tar or pharmaceutically acceptable salts, respectively； provided, however, that the compounds involved are not selected from (R) - N - (6-methyl-5 - (4-methyl-1h-imidazol-1-il) piridin-2-il-4, 5-tetrahydropirine [3, 2-F] [1, 4-8]；(R) 4] [4-4-4-4] [4-4-4] [4-4-4] [4-4-4] [4-4-4] 1, 4) oxazepin-8-amine； N - (6-methyl-5 - (1-methyl-1h-pirazol-4-il) piridin-2-il) - 4-methyl-2 - (6-methylpiridin-2-il) - 2, 3, 4, Hydrazine [3, 2-F] [1, 4] oxazen-8-amine；Derivados de tetrahidropirido[3,2-f][1,4]oxazepin-8-amina, composición farmacéutica.Reivindicación 1: Un compuesto de fórmula (1) donde: R1 se selecciona de hidrógeno, alquilo C1-3, -C(O)CH3, -CH2CH2OCH3, -C(O)N(CH3)2 y -CH2CN； R2 se selecciona de alquilo C2-4 (opcionalmente sustituido con uno o varios sustituyentes seleccionados independientemente de flúor e hidroxi), fenilo, heteroarilo de 5 ó 6 miembros, carbociclilo C3-6 y heterociclilo C4-6 (donde el fenilo, heteroarilo de 5 ó 6 miembros, carbociclilo C3-6 y heterociclilo C4-6 están
