Caroline Leriche;Christine Charon;Didier Roche;Denis Carniato;Liliane Doare
发明人:
Caroline Leriche,Denis Carniato,Didier Roche,Christine Charon,Liliane Doare
申请号：
US12991016
公开号：
US08546575B2
申请日:
2009.04.08
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to NIP thiazole derivatives of formula (I) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11-β-HSD-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.
