PROBLEM TO BE SOLVED: To provide a method for producing efficiently a nano fluid dispersion having improved maintainability, concerning a nano fluid dispersion of a slightly-soluble material such as curcumin and its kind.SOLUTION: In a production method of a nano fluid dispersion, a target 1 containing a slightly-soluble material 3 is irradiated with an ultrashort pulse laser beam 23 having a pulse time width of 1 fsec to less than 200 psec to perform laser ablation, in a liquid medium 2 containing host molecules 4 such as a cyclodextrin-based compound, capable of forming an inclusion complex 5 of the slightly-soluble material 3.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2016,JPO&INPIT【課題】例えばクルクミン類のような難溶性物質のナノ分散液に関し、保存性が改善されたナノ分散液を効率よく製造する方法を提供する。【解決手段】難溶性物質3の包接体5を形成可能な、例えばシクロデキストリン系化合物のようなホスト分子4を含む液状媒体2中で、難溶性物質3を含むターゲット1にパルス時間幅が1fsec~200psec未満の超短パルスレーザレーザ光23を照射してレーザアブレーションすることを含むナノ分散液製造方法。【選択図】図1