Carolyn R. Bertozzi,Mary Sloan Siegrist Palmore,John C. Jewett,Chelsea G. Gordon,Peyton Shieh
申请号:
US15704977
公开号:
US20180000929A1
申请日:
2017.09.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria or peptidoglycan; and methods of using the modified bacteria or peptidoglycan. The modified D-amino acids include a bioorthogonal functional group such as an azide, an alkyne or a norbornene group. Also provided are modified peptidoglycans conjugated to a molecule of interest via a linker.