IMMUNOSTIMULATORY OLIGONUCLEOTIDE SEQUENCE AND USES THEREOF

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专利权人:

发明人:

LOPEZ RICARDO AUGUSTIN

申请号：

IN3773/DELNP/2004

公开号：

IN252038B

申请日:

2004.11.30

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

The present invention provides an immunostimulatory oligonucleotide having 24 to 100 nucleotides, comprising the nucleotide sequence TCATCATTTTGTCATTTTGTCATT, that has the ability to stimulate the immune response of animals including humans. The stmulation of the immune response is characterized by stimulation of proliferation, differentiation, cytokine production and antibody production in B-cells and cell differentiation and cytokine production in plasmacytoid dendritic cells. The present invention further provides a pharmaceutical composition comprising said immunostimulatory oligonucleotide.

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