The present invention relates to a radioactive and impermeable biological composite material, which includes:10~40% wt. of calcium sulfate, 10~20% wt. of Ta2O5,and 40~80% wt. of polymer substrate. The present invention is aimed to improve the X-ray radiation permeability of the conventional implant material implanted human spineo, and form a " bioactive " ceramic composite material which is capable of forming cavities in vivo.本發明一種具輻射不通透性之生物活性複合材料,該複合材料包含:重量百分比10%~40%的硫酸鈣、重量百分比10%~20%的五氧化二鉭以及重量百分比40%~80%的高分子基材。據以達到改善習知的植入人體的脊椎復位材料的X光輻射通透性以及可於生物體內自行形成孔洞的『具生物活性』陶瓷之複合材料特性。