Florence M. Hofman,Raquel M.S. Ferreira,Steven L. Giannotta,Thomas C. Chen
申请号:
US16432532
公开号:
US20190367918A1
申请日:
2019.06.05
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention relates to compositions, methods and kits for using Argonaute-2 (Ago-2) as a systemic carrier to deliver a miRNA to an endothelial cell. The invention also relates to compositions, methods and kits for inhibiting angiogenesis and/or treating a condition by using Ago-2 as a systemic carrier to deliver a miRNA to an endothelial cell. The condition includes but is not limited to brain vascular diseases and brain tumors.