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Pyrazolopyrimidine derivatives
专利权人:
第一三共株式会社
发明人:
大薄 悟,天花寺 厚,池田 政浩,永田 親弘,島田 多堅,柴田 憲宏
申请号:
JP2008535335
公开号:
JP5252636B2
申请日:
2007.09.14
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
Problem to be Solved To provide a novel compound inhibiting the effect of HSP90, in particular a novel compound inhibiting the function of HSP90 as a chaperone protein and having antitumor activity. Solution The present invention provides a pyrazolopyrimidine compound represented by the formula (1) having various substituents which inhibits the ATPase activity of HSP90 and which has antitumor activity, an HSP90 inhibitor comprising the compound represented by the formula (1), a medicament comprising the compound represented by the formula (1), an anticancer agent comprising the compound represented by the formula (1), a pharmaceutical composition comprising the compound represented by the formula (1) and a method for treating cancer using the compound represented by the formula (1).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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