CureVac AG;Boehringer Ingelheim International GmbH
发明人:
Regina HEIDENREICH,Katja FIEDLER,Mariola FOTIN-MLECZEK,Aleksandra KOWALCZYK,Knut ELBERS,Melanie WURM
申请号:
US16494422
公开号:
US20200085944A1
申请日:
2018.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to the field of biomedicine, and in particular to the field of therapeutic nucleic acids. The present invention provides a combination of an RNA encoding an epitope and immune checkpoint inhibitors. A pharmaceutical composition, vaccine, and kit-of-parts comprising said combination are also provided. Furthermore, the present invention relates to the combination, (pharmaceutical) composition, vaccine or kit-of-parts for use in medicine, and in particular in the treatment and/or prophylaxis of cancer, infectious diseases and other diseases and disorders.