Maria Del Carmen Fernandez Becerra;Hernando Antonio Del Portillo Obando;Lorena Martin Jaular
发明人:
Hernando Antonio Del Portillo Obando,Lorena Martin Jaular,Maria Del Carmen Fernandez Becerra
申请号:
US13519527
公开号:
US20120321676A1
申请日:
2010.12.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention belongs to the field of vaccines for the prevention and prophylaxis against malaria, more specifically it relates to exosomes isolated from reticulocytes infected with Plasmodium sp., to methods for obtaining them and to the use thereof for the prevention and prophylaxis against malaria as well as to its use for the discovery and identification of novel Plasmodium antigens. The invention also refers to artificial exosomes comprising Plasmodium sp. antigens. Finally, the invention refers to specific antigens discovered by means of the exosomes obtained from reticulocytes infected with Plasmodium sp.