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NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION
专利权人:
Vladimir SEREBRYANY;Brad BUCKMAN;John B. NICHOLAS;Scott SEIWERT
发明人:
Brad BUCKMAN,Vladimir SEREBRYANY,John B. NICHOLAS,Scott SEIWERT
申请号:
US13278984
公开号:
US20120101032A1
申请日:
2011.10.21
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The embodiments provide compounds of the general Formulae I, Ia, II, IIa, III, IIIa, IV, IVa, V, Va, VI and VIa, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
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