Hai Soo Lee,Ok Pho Zee,Joa Sub Oh,Eun Kyung Ahn,Jung A. Lee,Seong Su Hong
申请号：
US13520161
公开号：
US20130102554A1
申请日:
2010.12.30
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to a composition for treatment of obesity using a wheat bran extract or a tachioside or 9,12,13-trihydroxy-10(E)-octadecenoic acid, an active ingredient isolated therefrom. The wheat bran extract or the active ingredients inhibit the expression of PPARγ, C/EBRα and ADD1/SREBP1c, transcription factors which inhibit the differentiation of adipocyte progenitor cells to adipocytes, promoted by insulin, inhibit the accumulation of fats, and are centrally involved in the differentiation of adipocytes.
