LI, MING HSIN,李铭忻,李銘忻,CHIU, SHU PEI,邱淑佩,邱淑珮,CHANG, CHIH HSIEN,张志贤,張志賢,LEE, TE WEI,李德伟,李德偉
申请号:
TW102116958
公开号:
TW201442730A
申请日:
2013.05.14
申请国别(地区):
TW
年份:
2014
代理人:
摘要:
The present invention provides a Re-188-liposome automated synthesis apparatus, which comprises: configuring respective unit modules together and executing an automation procedure through a control software, so as to complete the four stages needed in the present invention: marking reaction, embedding reaction, separation/purification, and adjustment/filtration. When this device is in use, it is only necessary to place the reaction drugs into a specific reaction flask, turn on the power and use the gas pressure regulating valve to introduce reactive gases to facilitate the adjustment of the desired pressure. After starting the operating system of the present invention, an automated drug preparation procedure can be completed in a short time, it can be used in clinical diagnosis and treatment, and can save the production cost and avoid pollutions caused by manual operation.本發明提供一種錸-188-微脂體(Re-188-Liposome)自動化合成裝置,其係包括將各單元模組配置在一起,並藉由控制軟體執行自動化程序,以完成本發明之方法所需的標誌反應、包埋反應、分離純化以及調劑過濾共四個階段。使用本裝置時,僅需將反應藥品放入特定反應瓶中,打開電源並以壓力調節閥通入反應用之氣體以利調節所需壓力。啟動本發明之操作系統後,可在短時間內自動化完成藥物製備程序,提供臨床診斷與治療使用,可節省生產成本及防止人工操作所引起之污染。RL1‧‧‧產品瓶G1‧‧‧反應瓶T1‧‧‧暫存瓶F1‧‧‧濾膜W1‧‧‧廢液瓶R1~R6‧‧‧第一至第六試劑瓶P1~P8‧‧‧第一至第八微量泵浦V1~V7‧‧‧第一至第七電磁閥C1~C3‧‧‧PD-10凝膠過濾管柱