This invention provides a dry powder inhaler comprising : a dry powder medicament comprising fluticasone propionate salmeterol xinafoate and a lactose carrier wherein the delivered dose of fluticasone propionate per actuation is less than 100 µg and wherein the dose provides a baseline adjusted FEVin a patient of more than 150 mL within 30 minutes of receiving the dose. A method of treating a patient includes administering to a patient a dry powder medicament having fluticasone propionate salmeterol xinafoate and a lactose carrier wherein the delivered dose of fluticasone propionate per actuation is less than 100 pg and wherein the dose provides a baseline adjusted FEV in a patient of more than 150 mL within 30 minutes of receiving the dose.
