Bergmann, John E.,Cutshall, Neil S.,Demopulos, Gregory A.,Florio, Vincent A.,Gaitanaris, George,Gray, Patrick,Hohmann, John,Onrust, Rene,Zeng, Hongkui
申请号:
AU2013202067
公开号:
AU2013202067A1
申请日:
2013.03.22
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2013202067A120130411.pdf#####ABSTRACT A method of treating a movement abnormality associated with the pathology of a neurological movement disorder, such as Parkinsons disease or Restless Leg(s) Syndrome by administering a therapeutically effective amount of a PDE7 inhibitory agent. An aspect of the invention provides 5 for the administration of a PDE7 inhibitory agent in conjunction with a dopamine agonist or precursor, such as levodopa. In another aspect of the invention, the PDE7 inhibitory agent may be selective for PDE7 relative to other molecular targets (i) known to be involved with the pathology of Parkinsons disease or (ii) at which other drug(s) that are therapeutically effective to treat Parkinsons disease act. 10