BERGMANN John E.,BERGMANN John E.,CUTSHALL Neil S.,CUTSHALL Neil S.,DEMOPULOS Gregory A.,DEMOPULOS Gregory A.,FLORIO Vincent A.,FLORIO Vincent A.,GAITANARIS George,GAITANARIS George,GRAY Patrick,GRAY
申请号：
SI201031772
公开号：
SI2427193T1
申请日:
2010.05.03
申请国别(地区):
SI
年份:
2018
代理人:
摘要：
A method of treating a movement abnormality associated with the pathology of a neurological movement disorder, such as Parkinsons disease or Restless Leg(s) Syndrome by administering a therapeutically effective amount of a PDE7 inhibitory agent. An aspect of the invention provides for the administration of a PDE& inhibitory agent in conjunction with a dopamine agonist or precursor, such as levodopa. In another aspect of the invention, the PDE7 inhibitory agent may be selective for PDE7 relative to other molecular targets (i) known to be involved with the pathology of Parkinsons disease or (ii) at which other drug(s) that are therapeutically effective to treat Parkinsons disease act.
