KIM, YOUNG JU,김영주,YEON, YOUNG EUN,연영은,JANG, BONG GEUN,장봉근,HAN, BEOM KU,한범구,KIM, HYUN IL,김현일,PARK, CHARL SE,박철세
申请号:
KR1020160176994
公开号:
KR1018713380000B1
申请日:
2016.12.22
申请国别(地区):
KR
年份:
2018
代理人:
摘要:
The present invention relates to: a novel bacteriophage EC14 having unique extinction capacity to a pathogenic colon bacillus, specifically, an enterotoxigenic E. coli (ETEC) a pharmaceutical composition for preventing or treating an infectious disease due to the pathogenic colon bacillus including the bacteriophage an antibacterial composition a composition for being added to feed a feed including the same a disinfectant or a cleaning agent including the same and a method for preventing or treating an infectious disease due to the pathogenic colon bacillus, including a step of injecting the bacteriophage to a subject. According to the present invention, the method for preventing or treating the infectious disease due to the pathogenic colon bacillus using the bacteriophage EC14 has very high specificity on an avian pathogenic colon bacillus included in the pathogenic colon bacillus, specifically, the enterotoxigenic E. coli in comparison with existing chemicals such as antibiotics. Also, the bacteriophage EC14 is strong on physicochemical stimulation and has excellent bacteriolytic activity by being increased in bacteria following infection by the avian pathogenic colon bacillus. Also, according to the present invention, the bacteriophage EC14 does not infect other hosts except for the bacteria, such as a person, an animal, and a plant. So, the bacteriophage EC14 can solve a problem of an antibiotic resistant bacteria due to abuse of the antibiotic, a remaining problem of the antibiotic in food, and a problem of a wide host range. Therefore, according to the present invention, the bacteriophage EC14 can be variously used for treatment or prevention of infectious disease due to the pathogenic colon bacillus, the antibacterial composition, the composition for being added to the feed, the feed, and the field of the disinfectant or cleaning agent.본 발명은 병원성 대장균, 특히 장독소성 대장균(Enterotoxigenic E. coli, ETEC)에 특이적인 사멸능을 갖는 신규 박테리오파지 EC14, 상기 박테리오파지를 포함하는 병원성 대장균에 의한 감염성 질병의