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pharmaceutical compositions and / or nutraceutiche containing active substances insoluble in water and process for obtaining them.
专利权人:
LABOMAR S.R.L.
发明人:
FRATTER ANDREA,BERTIN WALTER
申请号:
ITMI20101119
公开号:
IT1400695B1
申请日:
2010.06.21
申请国别(地区):
IT
年份:
2013
代理人:
摘要:
Herein described are solid compositions in form of powders or granulates wherein an active ingredient insoluble or poorly soluble in water and/or thermolabile and/or having unpleasant organoleptic properties is dispersed in a lipid matrix containing a triglyceride, a polyoxyethylene sorbitan ester and ascorbyl palmitate. These compositions can be used, mixed with possible excipients or carriers for pharmaceutical or nutritional use, for the preparation of pharmaceutical or nutraceutical compositions in the form of powders, granulates or tablets of pleasant taste and which can form extemporaneous nano-emulsions upon dispersion in water. Further described is a method for preparing the compositions of the invention; such method is particularly advantageous in that it can be conducted at ambient temperature, without providing for any heating of the phases and/or vigorous mechanical stirring or dry or wet granulation techniques, thus avoiding the degradation of the active ingredient and reducing the process costs.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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