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4-pyridinone compounds and their use for cancer
专利权人:
Robert C. Livingston
发明人:
Robert C. Livingston,William P. Gallagher
申请号:
US12863713
公开号:
US08558000B2
申请日:
2009.01.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed herein is a process for preparing a compound of Formula (I), comprising the steps of: (a) reacting an aniline compound of Formula (II) and an carboxylic acid compound of Formula (III) or an activated carboxylic acid compound thereof, to provide a compound of Formula (IV) and (b) converting said protected amine group attached to said compound of Formula (IV) to an amine group to provide said compound of Formula (I) wherein PAm is a protected amine group. Processes to prepare the compounds of Formulae (II), (III), and (IV) are also disclosed.
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