The invention relates to tetrahydropyridoindole derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions comprising one or more of those compounds and methods of treatment comprising administration of said compounds.本發明係關於四氫吡啶并吲哚衍生物及其在醫藥組合物製備中作為活性成分之用途。本發明之目的亦關於製備該化合物之方法、包括一或多種此等化合物之醫藥組合物及包括投予該化合物之治療方法。