[Problem] To provide a decontamination device that employs peracetic acid and is highly safe and effective, and a decontamination method using said decontamination device.[Solution] A decontamination device A is a device for sterilizing the inside of a facility or the inside of a device, installed in said facility, for handling or culturing cells, tissue, culture media, sterile reagents, microorganisms and the like, is installed in a decontamination area, and comprises: a dry fog generating machine 1 which generates a dry fog from a peracetic acid mixed solution containing low concentration peracetic acid and sprays the same into the decontamination area； a humidity sensor 3 which is installed in the decontamination area to measure the humidity in the decontamination area； a gas recovery machine 4 which is installed in the decontamination area to recover gas in the decontamination area； and a control device 6 which controls spraying by the dry fog generating machine 1 and the gas recovery operation performed by the gas recovery machine 4 on the basis of information from the humidity sensor 3. A main control and monitoring device 7 which controls the control devices 6 of one or a plurality of the decontamination devices A is installed outside the decontamination area.La présente invention concerne un dispositif de décontamination qui utilise de l'acide peracétique et est très sûr et efficace, et un procédé de décontamination utilisant ledit dispositif de décontamination. Le dispositif de décontamination (A) est un dispositif servant à stériliser l'intérieur d'une installation ou l'intérieur d'un dispositif installé dans ladite installation, en vue de la manipulation ou de la mise en culture de cellules, de tissus, de milieux de culture, de réactifs stériles, de micro-organismes et analogue, ledit dispositif étant installé dans une zone de décontamination et comprenant : une machine à brouillard sec (1), qui génère un brouillard sec à partir d'une solution mixte d'a
