A coupling device (1) for a tubular arrangement (2) for medical use comprising a first connector part (3) and a second connector part (5) and, an engagement/disengagement member (23) for at least assisting in engaging and disengaging the engagement between said connector parts, and the first connector part (3) comprises at least two female connecting portions (9) arranged in a first connector surface (7) and a guiding edge (11) protruding from the first connector surface (7) arranged around the at least two female connecting portions (9) and the second connector part (5) comprises at least two male connecting portions (19) arranged in a second connector surface (17), and wherein at least one of the first connector part (3) and the second connector part (5) comprises a locking element (13) arranged to rotatably engage with the engagement/disengagement member (23).