Medical implant devices are prepared from a polymeric material and a release agent, where the device is a molded, reservoir implant, and the release agent has a molecular weight (MW) of at least 1000. The release agent may be a non-ionic surfactant such as Brij 35, polyoxyetheylene(20)sorbitan trioleate, Tween 20, Tween 80, vitamin E TPGS, and a mixture of any two or more thereof. Hydrated implants may have a surface area of about 500 mm2or greater.由聚合物質及釋出劑製備之一種醫學植入物元件,該元件為一模製的儲存區植入物,該釋出劑分子量(MW)為至少1000。釋出劑可為非離子性界面活性劑,諸如Brij 35、聚氧乙烯(20)去水山梨醇三油酸鹽、Tween 20、Tween 80、維他命E TPGS,及其等兩種以上之混合物。水合植入物可具有約500 mm2或更大的表面面積。