БАУДНЕР Барбара (IT),ОХЕЙГАН Дерек (US),СИНГХ Манмохан (US),БУФАЛИ Симоне (IT)
申请号：
RU2015106930
公开号：
RU2015106930A
申请日:
2013.09.06
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. An immunogenic composition comprising (a) an immunogen meningococcus serogroup B, (b) at least one diphtheria toxoid, tetanus toxoid and / or pertussis toxoid, and (c) an adjuvant selected from (i) aluminum salts and combinations TLR agonist or (ii) an emulsion type "oil in water" .2. Composition according to Claim. 1, wherein the component (b) includes all three of diphtheria toxoid, tetanus toxoid and pertussis anatoksina.3. Composition according to claim. 2, wherein the component (b) includes more of diphtheria toxoid, tetanus toxoid than as measured in Lf.4 units. Composition according to claim. 2, wherein the component (b) comprises less of Diphtheria toxoid, tetanus toxoid than as measured in Lf.5 units. An immunogenic composition comprising (a) serogroup B meningococcus immunogen and (b) diphtheria toxoid, tetanus toxoid and pertussis toxoid, wherein the diphtheria toxoid is present in an excess amount compared to tetanus toxoid as measured in Lf.6 units. A composition according to claim. 5 comprising adyuvant.7. Composition according to claim. 6, wherein the adjuvant comprises (i) one or more aluminum salts, (ii), or TLR agonist (iii) an emulsion of "oil in water" .8. An immunogenic composition comprising (a) serogroup B meningococcus immunogen and (b) diphtheria toxoid, tetanus toxoid and pertussis toxoid, wherein the tetanus toxoid is present in an excess amount compared to diphtheria toxoid as measured in Lf.9 units. A composition according to claim. 8, comprising adyuvant.10. Composition according to claim. 9, wherein the adjuvant comprises (i) one or more aluminum salts, (ii), or TLR agonist (iii) an emulsion of "oil in water" .11. A composition according to any one of the preceding claims, comprising component (a) meningococcal1. Иммуногенная композиция, включающая (а) иммуноген менингококка серогруппы В, (b) по меньшей мере один из дифтерийного анатоксина, столбнячного анатоксина и/или коклюшного анатоксина и (с) адъювант, выбранный из (i) комбинац
