Provided herein are methods of using certain Hsp90 inhibitors in treating subjects who have experienced or are experiencing a traumatic brain injury, including lessening the short term impact of such TBI and/or reducing the risk of developing and/or the severity of long term after effects of such TBI.本文提供在治療已經歷或正在經歷創傷性腦損傷之個體時使用某些Hsp90抑制劑之方法,其包括減輕此類TBI之短期影響及/或降低此類TBI作用之後的長期發展風險及/或嚴重程度。