PROBLEM TO BE SOLVED: To provide novel peptides having freezing protection activity, and having excellent biomaterial protection activity having both high water solubility and high heat stability, based on antifreeze peptide, to provide biomaterial protective agents containing the peptides as an active ingredient, and to provide biomaterial protective methods.SOLUTION: The present invention relates to a peptide represented by the amino acid sequence of Asp-Thr-Ala-Ser-Asp-(Ala)7-Thr-(Ala)10-Thr-Ala-Lys-(Ala)3-Glu-(Ala)4-Thr-(Ala)4-Arg, or a peptide which has an amino acid sequence in which one or some amino acid residues are deleted, added, inserted or substituted in the peptide or which has an amino acid sequence 86% or more identical to the peptide and has biomaterial protection activity equivalent to the peptide.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】不凍ペプチドに基づく、凍結保護活性を有する、高い水溶性と熱安定性を兼ね備えた優れた生体材料保護活性を有する新規ペプチド及び該ペプチドを有効成分として含んでなる生体材料保護剤及び生体材料保護方法の提供。【解決手段】Asp-Thr-Ala-Ser-Asp-(Ala)7-Thr-(Ala)10-Thr-Ala-Lys-(Ala)3-Glu-(Ala)4-Thr-(Ala)4-Argのアミノ酸配列で表されるペプチド、又は1個から数個のアミノ酸残基の欠失、付加、挿入若しくは置換されたアミノ酸配列或いは86%以上の同一性を有するアミノ酸配列を有し、該ペプチドと同等な生体材料保護活性を有するペプチド。【選択図】なし
