Iminopyridine derivatives and uses thereof

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专利权人:

武田薬品工業株式会社

发明人:

吉田 雅都,須崎 智彦,小原 康久,久野 晴彦,長袋 洋,犀川 礼子,岡部 裕一,今井 重光

申请号：

JP2008540986

公开号：

JP5483880B2

申请日:

2007.10.22

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

Provided are an iminopyridine derivative having a selective ± 1D adrenergic receptor antagonistic action and useful as an agent for the prophylaxis or treatment of a lower urinary tract disease and the like, and a screening method for a compound having an ± 1D adrenergic receptor antagonistic action. An ± 1D adrenergic receptor antagonist containing a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof, and a method of screening for an agent having an ± 1D adrenergic receptor antagonistic action for the prophylaxis or treatment of a lower urinary tract disease, which includes measuring the bladder smooth muscle tension of rats with bladder outlet obstruction.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/