(R)-2-(2-aminothiazol-4-yl)-4-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetic acid anilide or its salt shows a potent bladder relaxation effect in isolated rat bladder smooth muscle relaxation test, dose-dependently lowers the contraction frequency of rhythmic bladder contractions in rat rhythmic bladder contraction measurement test and, moreover, prolongs the urination intervals in urination functions measurement test on cyclophosphamide-induced overactive bladder model rat. Owing to these effects, the above compound is useful as a remedy for ovaractive bladder.
