The inventors surprisingly found that specific oligosaccharides are capable of inhibiting viral replication through inhibiting NF-&kgrB activation. The invention thus pertains to a composition comprising pectin (in the form of digalacturonic acid, trigalacturonic acid, polygalacturonic acid), Arabinoxylan from rice bran, &bgr-glucan from bakers yeast, D-Ribose or mixtures there-of for inhibiting viral replication in a mammal with a viral disease.
