KURT DAVID HANKENSON,MICHAEL IRVING DISHOWITZ,JASON ALAN BURDICK,FENGCHANG ZHU,JAIMO AHN
申请号：
US14760371
公开号：
US20150352180A1
申请日:
2014.01.10
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed herein are compositions comprising an osteoinductive Notch ligand bound to at least one biocompatible substrate. Also disclosed are methods of treating patients in need of bone tissue formation through the administration of a composition comprising an osteoinductive Notch ligand bound to at least one biocompatible substrate. Further provided are methods of treating a patient in need of bone tissue formation comprising administering to said patient a composition comprising a nucleic acid molecule encoding a notch intracellular domain (NICD). Also disclosed are kits for promoting bone tissue formation.
