Luis Martinez-Sobrido,Aitor Nogales-Gonzalez,Colin Parrish
申请号：
US15753688
公开号：
US20180256703A1
申请日:
2016.08.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that one or more mutations in segment 4 of the viral genome produces a single cycle infectious CIV (sciCIV). The sciCIV does not allow for the production of infectious progeny, but is able to induce a CIV-specific immune response.
