Luis Martinez-Sobrido,Aitor Nogales-Gonzalez,Colin Parrish
申请号：
US15753671
公开号：
US10478489B2
申请日:
2016.08.19
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.
