PROBLEM TO BE SOLVED: To provide a prophylactic or therapeutic agent for night urination.SOLUTION: It is confirmed that a pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate compound or a salt thereof has an effective bladder capacity increasing activity and a sleep disorder ameliorating activity and also has an anti-diuretic activity which rely on a FAAH inhibiting activity thereof. Therefore, the pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate compound or the salt thereof can be used for the prevention or treatment of night urination which is believed to be caused by various causes such as increased night urine flow, the reduction in night bladder capacity and sleep disorder.COPYRIGHT: (C)2013,JPO&INPIT【課題】夜間頻尿の予防又は治療剤の提供。【解決手段】ピリジル 非芳香族含窒素へテロ環-1-カルボキシラート化合物又はその塩が、FAAH阻害作用に基づき、有効膀胱容量増大作用及び睡眠障害改善作用を有するだけではなく抗利尿作用を有することが確認された。従って、ピリジル 非芳香族含窒素へテロ環-1-カルボキシラート化合物又はその塩は、夜間多尿、夜間膀胱容量の低下、睡眠障害など多様な病因を有するとされる夜間頻尿の予防又は治療に使用できる。【選択図】なし
