A pulse oxygen system and methods for providing oxygen to a user are disclosed. An oxygen mask coupled to a metering valve is provided to a user. An oxygen prescription delivery amount is determined based on and as a function of a real-time operation condition. A metering valve timing is calculated based on the oxygen prescription delivery amount to obtain a pulse delivery time. A pressure and time regulated flow of the oxygen prescription delivery amount of pulsed oxygen is then dispensed to the oxygen mask for a duration of the pulse delivery time in response to detecting the user breathing through the oxygen mask.