您的位置: 首页 > 农业专利 > 详情页

Novel compounds Composition Comprising the Same for Preventing and Treating Inflammatory Diseases
专利权人:
KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY
发明人:
임정한,김일찬,한세종,윤의중,오현철,손재학,김윤철,이동호,권재영,이혜민,고원민,김동철,김관우,YIM, JOUNG HANKR,KIM, IL CHANKR,HAN, SE JONGKR,YOUN, UI JOUNGKR,OH, HYUN CHEOLKR,SOHN, JAE HAKKR,KIM, YOUN CHULKR,LEE, DONG HOKR,KWON, JAE YOUNGKR,LEE, HYAE MINKR,이
申请号:
KR1020160067785
公开号:
KR1017422380000B1
申请日:
2016.05.31
申请国别(地区):
KR
年份:
2017
代理人:
摘要:
TECHNICAL FIELD The present invention relates to a novel compound and a composition for preventing or treating an inflammatory disease containing the same as an active ingredient. More particularly, the present invention relates to a novel compound and a composition for preventing or treating an inflammatory disease comprising Aspergillus sp. Asperanin A, asperanin B, asperanin C, 5-prenyl-dihydrobarcocholine F and 5-prenyl-dihydrodoburumazine A, which have anti-inflammatory effects isolated from SF-5976, And a composition for preventing or treating an inflammatory disease containing the same. The present invention relates to an inflammatory disease comprising asperanin A, asperanin B, asperanin C, 5-prenyl-dihydrobarcocholine F or 5-prenyl-dihydrobromarin A according to the present invention as an active ingredient The composition for preventing or treating RA inhibits the proinflammatory cytokine and mediator production in RAW264.7 macrophages and BV2 microglia cells in association with the inflammatory reaction and thus can be usefully used for the prophylactic or therapeutic use of inflammatory diseases.본 발명은 신규 화합물, 및 이를 유효성분으로 함유하는 염증질환 예방 또는 치료용 조성물에 관한 것으로, 보다 상세하게는 해양 진균 Aspergillus sp. SF-5976에서 분리된 항염증 효과를 갖는 아스페라닌 A, 아스페라닌 B, 아스페라닌 C, 5-프레닐-디히드로바리에콜로린 F 및 5-프레닐-디히드로우브루마진 A, 및 이를 함유하는 염증질환 예방 또는 치료용 조성물에 관한 것이다. 본 발명에 따른 아스페라닌 A, 아스페라닌 B, 아스페라닌 C, 5-프레닐-디히드로바리에콜로린 F 또는 5-프레닐-디히드로우브루마진 A를 유효성분으로 함유하는 염증성 질환 예방 또는 치료용 조성물은, 염증반응과 관련하여 RAW264.7 대식세포와 BV2 미세아교세포에서 전염증성 사이토카인 및 매개체 생성을 억제하므로, 염증성 질환의 예방 또는 치료용도로 유용하게 사용될 수 있다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充