Cha, Mi Young,Kang, Seok Jong,Kim, Mi Ra,Lee, Ju Yeon,Jeon, Ji Young,Jo, Myoung Gi,Kwak, Eun Joo,Lee, Kwang Ok,Ha, Tae Hee,Suh, Kwee Hyun,Kim, Maeng Sup
申请号:
AU2014202057
公开号:
AU2014202057A1
申请日:
2014.04.11
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2014202057A120140508.pdf#####ABSTRACT Disclosed herein are furan- or thiophene-fused pyrimidine derivatives which selectively inhibit cancers or tumours induced by an epidermal growth factor receptor (EGFR) tyrosine kinase or a mutant thereof with reduced adverse side effects. Also disclosed are pharmaceutical compositions for preventing or treating cancers, tumours, inflammatory diseases, autoimmune diseases or immunologically mediated diseases comprising the fused pyrimidine compounds.