A kind of multiply modified derivatives of gelatin having not only the structureof formula (I) but also one of structures of formula (II), (III), and (IV) as well.In the formulas, G refers to gelatin residue comprising A type, B type and the typeof gene restructuring； R1 refers to alkylene, or a linkage group with amide； R2refers to alkyl, or aryl； R3 refers to alkylene； R4 refers to carboxyl or carboxylate.The multiple modifying ways of gelatin comprise the modifying way of hydrophobicactivating the amide of branch amine group of gelatin, the modifying way of carboxylatingthe amide of branch amine group of gelatin, the modifying way of thiolating thebranch carboxyl group of gelatin, and the modifying way of thiolating the modifiedproduct of carboxylating the amide of branch amine group of gelatin. The multiplymodified derivatives of gelatin have versatile chemical structures and multi-functions.The multiply modified derivatives of gelatin linked with crosslinking agentcan provide crosslinked gelatin material. The crosslinked gelatin materialcan be used for matrix of bacterial growth.
