Insert and a device housing the first configured base is adapted to be carried on a patient (206), so that engagement and disengagement operatively (206) the base and (280) A system, device housing of the first (280) is, the first is movable within at least a portion of (280) the device housing of the first between the advanced position and the retracted position at least with the (260) the carrier body, the carrier body of the first (260) is oriented to inserted into the skin of the patient when moving (260) the carrier body of the first to the advanced position from the retracted position It is intended for supporting (246) the penetrating member at a position that is further insertion system die is configured to be disengaged and operatively engaging with the (280) device housing of the first and a device housing 2 (291), the device the second housing (291) is positioned to move within at least a portion of (291) the device housing of the second between the advanced position and the retracted position at least with the carrier body of a second, which is the (298), the carrier said second body (298) is a engageable operatively and (260) the carrier body of the first device the second housing ( further comprising a (293) drive mechanism disposed device housing the second (291) interior, said drive mechanism (293), 291) is inserted through the skin of the patient at least a portion of the piercing member (246) It is an insertion system for providing a rotational force to, to move toward the advanced position from the retracted position the carrier body of the first (260).患者に担持されるように適合されたベース(206)と、前記ベース(206)と動作可能に係合および係合解除されるように構成された第1のデバイスハウジング(280)とを備える挿入システムであって、前記第1のデバイスハウジング(280)が、少なくとも後退位置と前進位置の間で前記第1のデバイスハウジング(280)の少なくとも一部分の内部で移動するように配置された第1のキャリア本体(260)を備え、前記第1のキャリア本体(260)が、前記後退位置から前記前進位置への前記第1のキャリア本体(260)の移動時に前記患者の皮膚に挿通するように向けられた位置で穿刺部材(246)を支持するためのものであり、挿入システムがさらに、前記第1のデバイスハウジング(280)と動作可能に係合および係合解除されるように構成された第2のデバイスハウジング(291)を備え、前記第2のデバイスハウジング(291)が、少なくとも後退位
