A virus removal membrane for removing a virus from a solution containing a protein, wherein the virus removal membrane is provided with cellulose and has a primary-side surface that is supplied with a solution containing a protein, and a secondary-side surface from which a permeated liquid that has permeated the virus removal membrane is discharged, the bubble point of the virus removal membrane being 0.5-1.0 MPa, a solution containing metal colloids having a diameter of 30 nm being supplied from the primary side to the virus removal membrane and the metal colloids being captured by the virus removal membrane, and, when luminance is measured in a cross-section of the virus removal membrane, the value obtained by dividing the standard deviation of the area value of a spectrum of luminance displacement by the average value of the area value of the spectrum of luminance displacement is 0.01-0.30.