HYUN HEE KWAK,GHUN II LEE,YONG MAN PARK,HI CHANG YANG,TAE HYOUNG KIM,SUNG HEE LEE,SOO HYUNG KANG,MOOHI YOO,MI KYUNG SON,YOON JI KIM,BYONG MOON KIM
申请号：
BRPI0810140
公开号：
BRPI0810140A2
申请日:
2008.04.18
申请国别(地区):
BR
年份:
2014
代理人:
摘要：
Disclosed are biodegradable microspheres, capable of releasing a glucose-regulating peptide in a controlled manner, comprising a biodegradable polymer carrier with the glucose -regulating peptide encapsulated therein, and methods for the preparation thereof. In addition to ensuring high encapsulation efficiency and high stability of the encapsulated drug, the microspheres shows neither an initial burst effect nor incomplete release and allows the zero -order release of drugs over a prolonged period of time, thus improving the therapeutic effect of the drug.
