ANTIGEN BINDING PROTEIN, ISOLATED ANTIBODY, NEUTRALIZATION ANTIBODY, PHARMACEUTICAL COMPOSITION, NUCLEIC ACID MOLECULE, METHODS FOR MANUFACTURING ANTIGEN BINDING PROTEIN, FOR A NIM PRELIMINAR COLLAR AND, USE OF AN ANTIGEN BINDING PROTEIN.
SIMON MARK JACKSON,NIGEL PELHAM CLINTON WALKER,DEREK EVAN PIPER,BEI SHAN,WENYAN SHEN,JOYCE CHI YEE CHAN,CHADWICK TERENCE KING,RANDAL ROBERT KETCHEM,CHRISTOPHER MEHLIN,TERESA ARAZAS CARABEO,QIONG CAO
申请号：
BRPI0816117
公开号：
BRPI0816117A2
申请日:
2008.08.22
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
