Nguyen, Hung Q.,Lin, Fen-Fen,Bi, Xiao-Juan,McBride, Helen J.,Hu, Shaw-Fen Sylvia
申请号:
AU2010321832
公开号:
AU2010321832A1
申请日:
2010.11.19
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Disclosed is an isolated antigen binding proteins, such as but not limited to, an antibody or antibody fragment, that specifically bind to SEQ ID NO:4, the amino acid sequence of extracellular loop 2 (ECL2) of human Orai1. Also disclosed are pharmaceutical compositions and medicaments comprising the antigen binding protein, isolated nucleic acid encoding it, vectors and host cells useful in methods of making it, and methods of using it in treating disorders or diseases in patients.